Cruz Rivera, Yazeli E.

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Biosystems characterization, modeling and optimization
(2018-05) Cruz Rivera, Yazeli E.; Cabrera Ríos, Mauricio; College of Engineering; Mendez, Mayra; Seguel, Jaime; Cesaní, Viviana; Department of Industrial Engineering
There is a need for interdisciplinary work to better understand, represent, and make competitive decisions in regards of biosystems. In this work biosystems understanding is sought through statistical characterization, representation through statistical modeling, and decision-making through mathematical optimization, all within a biological framework. This thesis applies these concepts in an orderly fashion through three biosystems in particular: biofuel derived from algae, hairy vetch as a cover crop for corn, and the identification of important genes in Alzheimer’s Disease. The first case consists on supporting decision-making on lipid extraction to obtain biofuel from microalgae. The second case consists on defining how hairy vetch management and latitude affect the economics of hairy vetch. The last case consists of characterizing Alzheimer’s disease through differentially expressed genes using microarray experiments. After finding these genes an interaction is established within each other. These cases were identified independently but can be organized in the proposed framework.