Publication:
Improving surface-enhanced Raman scattering by the implementation of pillararenes on silver nanoparticles

dc.contributor.advisor Bezares, Francisco J.
dc.contributor.author Vázquez Pérez, Germán
dc.contributor.college College of Arts and Sciences - Sciences
dc.contributor.committee Marrero-Soto, Pablo J.
dc.contributor.committee Sánchez Quintero, Dilsom
dc.contributor.department Department of Physics
dc.contributor.representative Cabrera Ríos, Mauricio
dc.date.accessioned 2024-05-20T12:33:30Z
dc.date.available 2024-05-20T12:33:30Z
dc.date.issued 2024-05-09
dc.description.abstract Surface-enhanced Raman Scattering (SERS) spectroscopy is a highly sensitive and specific detection method. This technique is useful for sensing extremely small concentrations of analytes, that could be harmful for human health and food security. Therefore, it is of foremost importance to study methods that can enhance the sensing capabilities of SERS. This work presents an experimental and statistical analysis of optimal parameters for the synthesis of metallic nanoparticles, which are responsible for the enhancement of the Raman signal. After the parameter optimization, a layer of dimethoxy pillar[5]arene was deposited onto the Ag nanoparticles to study the selectivity of the technique. These are highly symmetric macrocycles that have the capacity to attract certain types of molecules into their central cavity. The layer of pillar[5]arenes was optimized for concentration and thickness, which allowed studying their capabilities to capture toxic analytes and detect them using SERS.
dc.description.abstract La espectroscopía de Raman aumentada por efectos de superficie (SERS por sus siglas en inglés) es un método de detección altamente sensitivo y especifico. Este resulta útil para detectar concentraciones extremadamente bajas de analitos, los cuales pueden ser dañinos para la salud humana y la seguridad alimentaria. Por lo tanto, es crucial estudiar maneras para mejorar las capacidades de la técnica. En este trabajo se presenta un análisis experimental y estadístico de parámetros óptimos para fabricar nanopartículas metálicas, las cuales son responsables del aumento en la señal de Raman. Luego de la optimización, se incorporó una capa de pilar[5]arenos para mejorar la selectividad de la técnica. Estos son macrociclos moleculares altamente simétricos que tienen la capacidad de atraer diferentes moléculas a su cavidad central. Se optimizó el grosor y la concentración de la capa de pilar[5]arenos, lo cual permitió estudiar sus capacidades para capturar analitos tóxicos y detectarlos mediante SERS.
dc.description.graduationSemester Spring
dc.description.graduationYear 2024
dc.description.sponsorship Research was financially supported by USDA-National Institute of Food and Agriculture. Grant Number: 2022-77040-37623
dc.identifier.uri https://hdl.handle.net/20.500.11801/3680
dc.language.iso en
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 International *
dc.rights.holder (c) 2024 German Vazquez Perez
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ *
dc.subject Nanophotonics
dc.subject Nanoparticles
dc.subject Pillararenes
dc.subject SERS
dc.subject Raman
dc.title Improving surface-enhanced Raman scattering by the implementation of pillararenes on silver nanoparticles
dc.type Thesis
dspace.entity.type Publication
thesis.degree.discipline Physics
thesis.degree.level M.S.
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