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dc.contributor.advisorOrtiz-Colón, Guillermo
dc.contributor.authorLópez-Soberal, Lorraine
dc.description.abstractThe presence of anthelmintic resistance was evaluated in 21 dairy commercial farms in Puerto Rico. A total of 407 heifers, with an average age of 9 months, were used to determine efficacy of three anthelmintic treatments: albendazole (ALB), doramectin (DOR) and ivermectin (IVM) in a fecal egg count reduction test (FECRT). Of all anthelmintics used, ALB proved to be the most effective treatment with a 67.47% of efficacy, followed by DOR with a reduction of 25.50%. Fecal egg count reduction (FECR) for IVM was -8.13. Fecal cultures from 10 of the evaluated farms were used to determine the predominant species of gastrointestinal nematodes present in evaluated dairy heifers. Cooperia spp. was the most predominant specie observed (70.88%) followed by Oesophagostomum radiatum (20.00%) and Haemonchus placei (4.63%). FECRT results indicate that anthelmintic resistance is a widespread problem in Puerto Rico.
dc.description.abstractSe evaluó la presencia de resistencia antihelmíntica en 21 fincas lecheras comerciales en Puerto Rico. Un total de 407 novillas, con una edad promedio de 9 meses, fueron utilizadas para determinar la eficacia de tres antihelmínticos: albendazol (ALB), doramectina (DOR) e ivermectina (IVM) en un “Fecal egg count reduction test” (FECRT). Albendazole resultó ser el tratamiento con mayor eficacia con un 67.47% de eficacia, seguido por DOR con una eficacia de 25.50%. La eficacia de IVM fue -8.13%, indicando un aumento en el número de huevos de nemátodos luego del tratamiento. Cultivos fecales de 10 de las fincas evaluadas fueron utilizados para determinar las especies predominantes de nemátodos gastrointestinales presentes. Cooperia spp. fué la especie más predominante observada (70.88%), seguido por Oesophagostomum radiatum (20.00%) y Haemonchus placei (4.63%). Los resultados obtenidos a partir de esta investigación demuestran la presencia de resistencia antihelmíntica en hatos lecheros en Puerto Rico.
dc.subjectAnthelmintic resistanceen_US
dc.subjectNematode parasiteen_US
dc.titleDetection of anthelmintic resistance in nematodes infecting dairy heifers and evaluation of molecular markers presumably associated with nematode parasite resistance in dairy heifersen_US
dc.rights.licenseAll rights reserveden_US
dc.rights.holder(c) 2013 Lorraine López Soberal.en_US
dc.contributor.committeePagán-Morales, Melvin
dc.contributor.committeeJiménez-Cabán, Esbal
dc.contributor.committeeGonzález, Olga
dc.contributor.committeeLatorre, José R.
dc.contributor.representativeOmar Soto, Jay Industryen_US
dc.contributor.collegeCollege of Agricultural Sciencesen_US
dc.contributor.departmentDepartment of Animal Scienceen_US

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