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dc.contributor.advisorCabrera-Ríos, Mauricio
dc.contributor.authorCruz-Rivera, Yazeli E.
dc.date.accessioned2019-05-07T17:50:43Z
dc.date.available2019-05-07T17:50:43Z
dc.date.issued2018-05
dc.identifier.urihttps://hdl.handle.net/20.500.11801/2124
dc.description.abstractThere is a need for interdisciplinary work to better understand, represent, and make competitive decisions in regards of biosystems. In this work biosystems understanding is sought through statistical characterization, representation through statistical modeling, and decision-making through mathematical optimization, all within a biological framework. This thesis applies these concepts in an orderly fashion through three biosystems in particular: biofuel derived from algae, hairy vetch as a cover crop for corn, and the identification of important genes in Alzheimer’s Disease. The first case consists on supporting decision-making on lipid extraction to obtain biofuel from microalgae. The second case consists on defining how hairy vetch management and latitude affect the economics of hairy vetch. The last case consists of characterizing Alzheimer’s disease through differentially expressed genes using microarray experiments. After finding these genes an interaction is established within each other. These cases were identified independently but can be organized in the proposed framework.en_US
dc.description.abstractEl trabajo interdisciplinario es necesario para entender, representar y tomar decisiones competitivas al respecto de biosistemas. Este trabajo se basa en utilizar métodos de caracterización, modelaje estadístico y toma de decisiones por medio de optimización matemática dentro del marco biológico. Este trabajo aplica estos conceptos de una forma ordenada en tres biosistemas: biocombustible obtenidos de algas, hairy vetch como cocultivo del maíz y la identificación de genes importantes en la enfermedad del Alzheimer. El primer caso consiste en apoyar la toma de decisiones en la extracción de lípidos para obtener biocombustible de algas. El segundo caso consiste en definir cómo el mantenimiento de hairy vetch y la latitud afecta su economía. El último caso consiste en caracterizar el Alzheimer por medio de genes que se diferencian en su expresión usando microarreglos e interacciones entre sí. Los casos han sido identificados independientemente, pero son organizados de acuerdo con el marco propuesto.en_US
dc.description.sponsorshipUSDA-NIFA Award 2015-38422-24064 sub award 1000000920; NIH MARC Assisting Bioinformatics Efforts at Minority Schools project 2T36GM008789en_US
dc.language.isoenen_US
dc.subjectMaximization of lipid production in algae - Vetch - Varietiesen_US
dc.subjectBiological systems - Vetch - Seeds - Viabilityen_US
dc.subjectMultidisciplinary design optimization - Biological systemsen_US
dc.subject.lcshBiological systemsen_US
dc.subject.lcshMathematical optimizationen_US
dc.subject.lcshBiomass energyen_US
dc.subject.lcshBioengineeringen_US
dc.titleBiosystems characterization, modeling and optimizationen_US
dc.typeThesisen_US
dc.rights.licenseAll rights reserveden_US
dc.rights.holder(c) 2018 Yazeli E. Cruz Riveraen_US
dc.contributor.committeeMendez, Mayra
dc.contributor.committeeSeguel, Jaime
dc.contributor.committeeCesaní, Viviana
thesis.degree.levelM.S.en_US
thesis.degree.disciplineIndustrial Engineeringen_US
dc.contributor.collegeCollege of Engineeringen_US
dc.contributor.departmentDepartment of Industrial Engineeringen_US
dc.description.graduationSemesterSpringen_US
dc.description.graduationYear2018en_US


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    Items included under this collection are theses, dissertations, and project reports submitted as a requirement for completing a graduate degree at UPR-Mayagüez.

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