Theses & Dissertations

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This collection is exclusively made up of theses, dissertations, and project reports submitted as a requirement for completing a graduate degree at UPR-Mayagüez. If you are a UPRM graduate student and you are looking for information related to the deposit process, please refer to https://libguides.uprm.edu/repositorioUPRM/tesis

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Now showing 1 - 5 of 3010
  • Publication
    Dinah's rape as narrative and ideological crossroads: A revisionist critique and alternate outcome
    ( 2024-05-14) Rivera Betancourt, Loida E ; Stephen, Gregory K. ; College of Arts and Sciences - Art ; Irizarry Rodriguez, Jose ; Cordero Rios, Hugo ; Department of English ; Rodriguez, Grisell
    Dinah’s Alternative Narrative was developed as an exercise for writing fiction starting with the Bible as literature. The story presents a different ending: the marriage of Dinah and Shechem. This alternative outcome provides a rescue of Dinah’s voice, that empowers her to decide what to do with her life and with whom. The narrative reverses the misogynistic and xenophobic intervention of Dinah’s brothers. I consider this story as a watershed in Hebrew identity as held by the Priestly/Redactor version of Genesis 34 that has been regarded as the official version. Dinah’s empowerment as qedeshah is a challenge thrown to a term in ancient Israel weighted with misconceptions and prejudice created by the Priestly/Redactor in a Deuteronomic context, against the cultic functions of these women and exclude them from Temple service. To convey a plausible and realistic narrative, I considered the latest biblical scholarship, including feminist studies, archeological, ethnographic, and linguistic inputs
  • Publication
    Study of the electric interactions in peptide-membrane interaction using molecular dynamics simulations
    ( 2024-05-09) Quintana Jaramillo, Thalia ; Ramos, Rafael A. ; College of Arts and Sciences - Sciences ; Roura Dávila, Erick A. ; Santana-Colón, Samuel ; Department of Physics ; Quintero Mendez, Raiza R.
    Inducing an increase in the permeability of biomembranes has become an attractive alternative for developing new treatments against cancer cells or bacteria. Two techniques to increase permeability are: through the application of electrical pulses, known as electroporation, or by facilitating the interaction of active peptides with biomembranes. Electroporation, however, has been limited by the need to apply high electric fields or prolonged exposure periods to achieve effective permeabilization, which can trigger significant side effects. On the other hand, understanding the mechanism of action of active peptides has presented challenges, making their design and implementation difficult. In the literature, it has been reported that the combination of cationic active peptides with electric pulses can reduce the intensity of the electric field required for membrane permeabilization. Nevertheless, the reasons behind this phenomenon have not yet been thoroughly explored. Based on this observation, we have used molecular dynamics simulations to investigate how the presence of a cationic peptide, specifically Cateslytin, can modify the impact of the electric field in the electroporation process. We found that when electrostatic interactions between the heads of the lipids and the cationic peptides, or ions, favor the reorientation of the lipid dipoles towards the direction of the field, the membrane permeabilization process occurs rapidly; thus, we suggest that this could explain the need for a lower intensity of the electric field.
  • Publication
    Trigger studies for the Emerging Jets analysis and machine learning for Tracker DQM at CMS experiment
    ( 2024-05-08) Fidalgo Rodríguez, Guillermo A. ; Malik, Sudhir ; College of Arts and Sciences - Sciences ; Marrero, Pablo ; Santana-Colón, Samuel ; Department of Physics ; Sierra, Heidy
    The Standard Model of Particle Physics (SM) has had a great track record over the decades. With the discovery of the top quark, the τ neutrino and the Higgs boson, the SM has proved it’s effectiveness and prediction prowess. Yet, it leaves behind open questions regarding problems like Dark Matter and thus a need for new physics. This has brought up many exotic searches in hopes of answering the questions that the SM has yet to address. To provide the necessary quality to search for new physics, physicists use the most complex machines ever designed. The preponderance of cosmological evidence suggests that the density dark matter energy density of the Universe is around 5 times the amount of regular baryonic matter, and hence, experimental searches have been developed to explain this. The CMS Collaboration has searched for signals of a dark matter model via the Emerging Jets analysis group. As with all experiments in High Energy physics, acquiring high quality of data is paramount to achieve groundbreaking science. The CMS experiment achieves the collection of it’s high quality data through the triggering and data acquisition systems put in place, but require manual labor to certify. In this work I present trigger efficiency studies relevant to the Emerging Jets analysis. Moreover, I present my work to improve the process of data certification in the DQM workflow implemented at the CMS Tracker DQM group. This work adds the automation of a new web application called the Machine Learning Playground designed to improve DQM shifter efficiency in data certification.
  • Publication
    Desarrollo de protocolo de multiplicación in vitro de Dioscorea rotundata cv Guinea Negro utilizando biorreactores de inmersión temporal
    ( 2024-05-10) Soto Morales, Josué ; Feliciano-Rivera, Merari ; College of Agricultural Sciences ; Morales Payán, Pablo ; Román-Paoli, Elvin ; Department of Agro-Environmental Sciences ; Rúa-de la Asunción, Armando
    Yam is one of the most important crops within the group of roots and tubers in Puerto Rico. Due to the lack of disease-free yam seed, local production has not increased in recent years. The objective of this research was to design a protocol for the micropropagation of Dioscorea rotundata cv Guinea Negro using temporary immersion bioreactors, as part of a plan for disease-free seed production. Through the experiments carried out, it was determined that using 1 g/L of Activated Charcoal (AC) during the in vitro establishment of yam resulted in higher multiplication rates than when AC is not used. It was also determined that in the multiplication stage using the temporary immersion bioreactor system (TIS) and 1 g/L of AC results in multiplication rates of 4 buds per plantlet. The plantlets developed in TIS had acclimatization survival rates greater than 95%. Adding 1 mg/L of 6-benzylaminopurine a during multiplication in TIS with AC resulted in a multiplication rate of 4.4 buds per plantlet. It was also determined that plants developed in TIS and then hardened can produce around 8 tubers per plant and half of these can be used directly to produce yam seeds. The results obtained in this research can serve as a basis for carrying out a disease-free seed production plan for farmers in Puerto Rico.
  • Publication
    Evaluación de puntos críticos mutacionales de lactato dehidrogenasa en ganado Senepol y Holstein que difieren en los genotipos del receptor de prolactina asociados con el pelo corto
    ( 2024-04-12) López Nieves, Lourdes Esther ; Pagán-Morales , Melvin ; College of Agricultural Sciences ; Sánchez-Rodríguez, Héctor L. ; Casas Guernica, Américo ; Department of Animal Science ; Carmona Negrón , José A.
    En este estudio evaluamos niveles de lactato en sangre y tejido de vacas Senepol (SEN) y Holstein (HO) genotipadas para el gen de pelo corto (homocigoto, heterocigoto y tipo salvaje). Determinamos polimorfismos de nucleótidos simples (PNS) en genes candidatos LDHs (lactato dehidrogenasa) (LDHA, LDHB, LDHC, LDHD) y se estimaron VCM (Valores de Cría Molecular) y TGP (Transmisión Genómica Predicha) para diferentes características. Además, observamos características de la médula del pelaje de estos animales. Valores inferiores de lactato fueron obtenidos en sangre (P=0.0164) y tejido (P=0.0365) para SEN homocigoto versus SEN heterocigoto, podría deberse al truncamiento del PRLR que provoca una inactivación de la expresión génica causando la reducción del tamaño del cabello. Pudimos mostrar asociaciones entre PNS en LDHs con ciertas características productivas, reproductivas y de tipo. No hubo efecto del genotipo para pelo corto sobre el diámetro de la médula e índice de la médula del área de la grupa (P=0,7259 y P= 0,0871, respectivamente), sin embargo, si en las costillas (P<0,0001) y hombros (P<0,0001). Estos resultados sugieren que el pelo corto en el ganado proporciona una mayor capacidad termorreguladora al combinar varios rasgos asociados con el pelo.