Search
Now showing items 1-9 of 9
BCS class II drug dispersions in hydroxypropyl methylcellulose solutions: The effect of polymer molecular weight and drug loading on the steady-state rheology of HPMC solutions
(2015)
Physical biopolymer gels are ideal candidates for the drug delivery of solid pharmaceutical drugs. Nevertheless, inclusion of particles may affect the rheology and gelation of these systems. In this work, we evaluate the ...
Structure and rheology of colloid-in-liquid crystal composites with novel anisotropic and hierarchical microstructures
(2015)
The Green's functions integral technique is used to determine the conduction heat transfer temperature field in flat plates, circular plates, and solid spheres with saw tooth heat generating sources. In all cases the ...
Rheological characterization of hydroxypropyl methylcellulose solutions: Gelation and molecular interactions with additives
(2015)
The discovery and development of highly hydrophobic drugs represents an additional challenge for the pharmaceutical industry, as traditional methods of encapsulation, administration, and dosage are not always appropriate. ...
Rheology and gelation of physical polymer gels
(2011)
The discovery of new potent and water-insoluble drugs has emphasized the need for novel drug-delivery systems and personalized dosification. Biopolymers solutions are an alternative over conventional methods since they can ...
Characterization of solid dispersions of hydroxypropyl cellulose films with griseofulvin via hot-melt extrusion
(2012)
Hot-melt extrusion has gained significance in the pharmaceutical industry to formulate solid dispersions. In a solid dispersion, poorly-water soluble drugs can be dispersed in an inert hydrophilic polymer matrix, improving ...
Rheology of rodlike nanoparticle suspensions in lyotropic liquid crystalline polymers
(2013)
Liquid crystalline polymers are ideal to develop oriented and anisotropic materials. The incorporation of a nanoparticle may improve or add properties to a matrix. Small concentrations of particles smaller than the liquid ...
Processing and characterization of nematic co-polymer Phba/Pet nanocomposite films via hot-melt extrusion
(2011)
In this research work, the effect of particle shape (i.e. rod-like, spherical and platellet) and concentration on the liquid crystalline structure of poly (4-benzoic acidco-ethylene terephthalate) (PHBA/PET) was evaluated ...
Single particle dynamics around the boundaries of nematic media
(2018-10-31)
Brownian motion of a colloid suspended in a lyotropic chromonic liquid crystal (LCLC's) leads to the description of the transport properties of the medium through a unification of theories where the confinement effect is ...
Rheological characterization of pharmaceutical gel formulations
(2010)
The aim of this research work was to study the rheological properties of an industrially relevant gelatin-based pharmaceutical formulation, since the rheology of the product provides
information regarding the structure ...