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BCS class II drug dispersions in hydroxypropyl methylcellulose solutions: The effect of polymer molecular weight and drug loading on the steady-state rheology of HPMC solutions
(2015)
Physical biopolymer gels are ideal candidates for the drug delivery of solid pharmaceutical drugs. Nevertheless, inclusion of particles may affect the rheology and gelation of these systems. In this work, we evaluate the ...
Characterization of solid dispersions of hydroxypropyl cellulose films with griseofulvin via hot-melt extrusion
(2012)
Hot-melt extrusion has gained significance in the pharmaceutical industry to formulate solid dispersions. In a solid dispersion, poorly-water soluble drugs can be dispersed in an inert hydrophilic polymer matrix, improving ...
Processing and characterization of nematic co-polymer Phba/Pet nanocomposite films via hot-melt extrusion
(2011)
In this research work, the effect of particle shape (i.e. rod-like, spherical and platellet) and concentration on the liquid crystalline structure of poly (4-benzoic acidco-ethylene terephthalate) (PHBA/PET) was evaluated ...
Rheological characterization of pharmaceutical gel formulations
(2010)
The aim of this research work was to study the rheological properties of an industrially relevant gelatin-based pharmaceutical formulation, since the rheology of the product provides
information regarding the structure ...