Now showing items 1-6 of 6
Immobilization of myoglobin from horse skeletal muscle (Mb) and hemoglobin (Hb1) from Lucina pectinata in hydrophilic polymer networks for H2S biosensor application
Hemeproteins are known for their spectroscopic properties which change during the binding of specific ligands. This project envisioned the immobilization of myoglobin from horse skeletal muscle (Mb) and hemoglobin I from ...
Carboxymethylation of dextran for surface modification of magnetite nanoparticles
Magnetite nanoparticles are currently studied for biomedical applications such as MRI, drug delivery, and magnetic fluid hyperthermia (MHF). These applications require nanoparticles with a suitable coating which provides ...
Studies of ferrite based magnetic nanoparticle uptake and magnetocytolysis effects on model cell cultures
Suspended ferrite magnetic nanoparticles are known to dissipate energy under an oscillating magnetic field. Such energy dissipation could be employed to locally raise temperature inside a tumor to 41-45°C (hyperthermia), ...
Towards the design of highly selective molecularly imprinted hydrogels for biosensor applications
Robust molecular recognition is essential to enhance the accuracy of diagnostic devices aiming for a better efficacy in the clinical treatment of patients. The molecular imprinting technique has gained attention to generate ...
Assessment of the stability and biological activity of our model proteins encapsulated in hydrogel membranes
Proteins are biological macromolecules which have a unique spatial conformation. This spatial conformation can be affected by extremes in pH, temperature, and organic solvents. Once this 3D spatial conformation is affected ...
Examination of the effect of PEG-Rich matrices in Multi Drug Resistance-Associated Protein (MRP) and Multi Drug Resistance (MDR) substrates transport utilizing the CaCo-2 Cell Model
Multidrug resistance (MDR) is responsible for the low absorption of a very wide range of drugs and has been recognized as one of the major hurdles in drug absorption. Crosslinked poly(ethylene glycol) based morphologies ...