Search
Now showing items 1-10 of 13
Optimization of a fluid bed dryer by the implementation of a model predictive controller
(2006)
Optimization of the drying operation requires a model containing the operating variables for fluid bed dryers (FBD). Modeling of FBD is still uncertain since the drying process is unpredictable and relies on empirical ...
Modeling and control of continuous tumble mixing of granular materials
(2005-06)
An approach to automatic control of a continuous tumble mixer of powders is presented. The control system is based on an ideal model that describes the mixer dynamics where the controlled variables are the outlet flow from ...
Experimental and numerical study of the continuous fluidized bed dryer
(2016)
Nowadays, batch fluid-bed drying is one of the most efficient drying methods for particulate material; but at the same time, it is the most energy consuming operation in the manufacturing of solid dosage forms. To minimize ...
Automation of a fluid bed dryer using multi-variant near infrared spectra and model predictive control
(2010)
The Fluidized Bed Dryer (FBD) is a common unit used in the pharmaceutical industry for its unique advantages when working with powders. With recent development in technology and environmental awareness, a desire to optimize ...
Effect of impeller speed on particle size distribution during high shear wet granulation process
(2010)
Wet granulation is the process where powders are mixed with a binder agent which is agitated with a mixer and forms a granulated product. This process is commonly used to better the processing characteristics of a powdered ...
Mixing of granular materials in an oscillatory shear mixer
(2009)
Mezclado es uno de los pasos más importantes en el manejo de los polvos en muchas industrias tales como en la industria química, metalúrgica, farmacéutica, alimenticia, etc., debido al gran efecto que tiene en la composición ...
Functionalization of inhalable particles by fluidized bed processing
(2008)
This work focused initially on the size reduction of naproxen sodium to less than 5 µm for inhalation applications. The second objective was the adhesion of naproxen sodium particles to micronized lactose particles with ...
Optimization of drying-end-points measurements for the automation of a fluidized-bed dryer using FT-NIR sprectroscopy
(2004)
Automatic control of a fluidized-bed drying process depends on the availability of
an in-line sensor to provide accurate measurements of product moisture content. Nearinfrared
(NIR) spectroscopy technology provides a ...
Modeling of growth kinetics of wet granulation in a high shear mixer by means of image processing and analysis
(2006)
Wet granulation is one of the most important operations where fine particles are
agglomerated into larger granules by adding a binder. The process is used in many chemical
industries including pharmaceutical, mineral ...
Determination of an empirical correlation for the mass transfer coefficients of pharmaceutical powders in a fluid bed layer
(2004)
The pharmaceutical industry has four basic operations to produce tablets: mixing, drying,
milling, and tablet pressing. Fluidized bed drying of the pharmaceutical powders is one of
the most efficient methods, which is ...