Now showing items 1-5 of 5
Optimization of a fluid bed dryer by the implementation of a model predictive controller
Optimization of the drying operation requires a model containing the operating variables for fluid bed dryers (FBD). Modeling of FBD is still uncertain since the drying process is unpredictable and relies on empirical ...
Modeling and control of continuous tumble mixing of granular materials
An approach to automatic control of a continuous tumble mixer of powders is presented. The control system is based on an ideal model that describes the mixer dynamics where the controlled variables are the outlet flow from ...
Functionalization of inhalable particles by fluidized bed processing
This work focused initially on the size reduction of naproxen sodium to less than 5 µm for inhalation applications. The second objective was the adhesion of naproxen sodium particles to micronized lactose particles with ...
Optimization of drying-end-points measurements for the automation of a fluidized-bed dryer using FT-NIR sprectroscopy
Automatic control of a fluidized-bed drying process depends on the availability of an in-line sensor to provide accurate measurements of product moisture content. Nearinfrared (NIR) spectroscopy technology provides a ...
Determination of an empirical correlation for the mass transfer coefficients of pharmaceutical powders in a fluid bed layer
The pharmaceutical industry has four basic operations to produce tablets: mixing, drying, milling, and tablet pressing. Fluidized bed drying of the pharmaceutical powders is one of the most efficient methods, which is ...