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BCS class II drug dispersions in hydroxypropyl methylcellulose solutions: The effect of polymer molecular weight and drug loading on the steady-state rheology of HPMC solutions
(2015)
Physical biopolymer gels are ideal candidates for the drug delivery of solid pharmaceutical drugs. Nevertheless, inclusion of particles may affect the rheology and gelation of these systems. In this work, we evaluate the ...
Polymeric nanocarriers for the enhancement of enzyme replacement therapy in lysosomal storage diseases: A proof of concept study
(2016)
Lysosomal Storage Diseases (LSDs) are a group of inheritable genetic diseases caused by mutant lysosomal enzymes, leading to the accumulation of undigested macromolecules in the lysosomes and causing increases in lysosome ...
Development of optimal iron oxide nanoparticles with increased heating capabilities for application in magnetic fluid hyperthermia
(2013)
Hipertermia de fluido magnético (MFH) a mostrado ser un método efectivo para la erradicación de células cancerosas. Esta técnica se basa en la absorción de nanopartículas magnéticas por parte de la célula seguido por la ...
Electrical characterization of sulfonated poly(styrene-isobutylene-styrene) triblock copolymer thin films
(2015-05)
Polymers are a fundamental part of electronic systems and are widely used due to their low cost, ease of processing, and their wide range of mechanical and electrical properties. They have traditionally been used as passive ...
Characterization of solid dispersions of hydroxypropyl cellulose films with griseofulvin via hot-melt extrusion
(2012)
Hot-melt extrusion has gained significance in the pharmaceutical industry to formulate solid dispersions. In a solid dispersion, poorly-water soluble drugs can be dispersed in an inert hydrophilic polymer matrix, improving ...
Novel synthesis and characterization of supported bimetallic films for hydrogen detection
(2014)
Continuous increase in energy demand and high levels of pollution generated by the existing energy sources have led researchers to explore other clean and renewable alternatives. Hydrogen gas (H2) is an option that has ...
Porous carbon-faujasite composites containing transition metals for aqueous phase adsorption applications
(2014)
Pharmaceutical and personal care products (PPCPs) have emerged in surface water in concentration levels enough to categorize them as “emerging contaminants” due to a lack of efficient wastewater treatment plant removal ...
Experimental and numerical study of the continuous fluidized bed dryer
(2016)
Nowadays, batch fluid-bed drying is one of the most efficient drying methods for particulate material; but at the same time, it is the most energy consuming operation in the manufacturing of solid dosage forms. To minimize ...
Catalytic conversion of CO2 to hydrocarbons
(2014)
The production of methanol and dimethyl ether via CO2 hydrogenation was studied using Pd catalysts supported on α-Ga2O3, α-β-Ga2O3 and β-Ga2O3 polymorphs. The catalytic activity improves with the increase in the content ...
Processing and characterization of nematic co-polymer Phba/Pet nanocomposite films via hot-melt extrusion
(2011)
In this research work, the effect of particle shape (i.e. rod-like, spherical and platellet) and concentration on the liquid crystalline structure of poly (4-benzoic acidco-ethylene terephthalate) (PHBA/PET) was evaluated ...