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Near infrared spectroscopic transmission measurements for pharmaceutical powder mixtures and theory of sampling (TOS) applied in pharmaceutical industry quality control (Qc) practices
(2015)
This thesis presents two projects that involve the implementation of near infrared spectroscopy. NIR spectroscopy is a fast and non-destructive spectroscopy that in combination with multivariate analysis is a very useful ...
High explosives detection in international mail using See-Through Raman Spectroscopy assisted by multivariate analysis
(2020-12-09)
See-Through Raman Spectroscopy (STRS) was used for the non-invasive, non-destructive sample analysis of high explosives (HEs) in mail envelopes or flats. The method resulted in a safe and rapid analysis of HEs: ammonium ...
Separation, identification, and quantification of explosives using thin layer chromatography coupled to mid-infrared laser spectroscopy
(2019-05-10)
The need for rapid instrumentation and methods for detection and identification of chemical and biological threat agents in national defense and homeland security settings has become an ever more important issue in modern ...
Remote infrared spectroscopy detection of highly energetic materials
(2015-12)
An Open-Path Standoff Detection System was designed using a telescope coupled to a EM27 Fourier Transform infrared spectrometer equipped with a mercury cadmium telluride (MCT) cryocooled detector. Samples of highly energetic ...
Analysis of prediction errors in partial least squares calibration models using near infrared spectroscopy by three experimental systems
(2019-05-14)
This dissertation is focused on understanding the absorption and scattering effects of solid materials in the near infrared (NIR) spectral region and their impact on the prediction errors observed in NIR calibration models ...
Development of Blend Uniformity Determination Methodologies in Continuous Pharmaceutical Manufacturing Processes using Near- Infrared Spectroscopy
(2020-04-17)
Pharmaceutical companies are responsible for the development of their own blend uniformity specifications and guidelines to assure uniformity and homogeneity. Blend uniformity is a critical in the manufacturing of solid ...