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BCS class II drug dispersions in hydroxypropyl methylcellulose solutions: The effect of polymer molecular weight and drug loading on the steady-state rheology of HPMC solutions
(2015)
Physical biopolymer gels are ideal candidates for the drug delivery of solid pharmaceutical drugs. Nevertheless, inclusion of particles may affect the rheology and gelation of these systems. In this work, we evaluate the ...
Polymeric nanocarriers for the enhancement of enzyme replacement therapy in lysosomal storage diseases: A proof of concept study
(2016)
Lysosomal Storage Diseases (LSDs) are a group of inheritable genetic diseases caused by mutant lysosomal enzymes, leading to the accumulation of undigested macromolecules in the lysosomes and causing increases in lysosome ...
Development of optimal iron oxide nanoparticles with increased heating capabilities for application in magnetic fluid hyperthermia
(2013)
Hipertermia de fluido magnético (MFH) a mostrado ser un método efectivo para la erradicación de células cancerosas. Esta técnica se basa en la absorción de nanopartículas magnéticas por parte de la célula seguido por la ...
Synthesis and characterization of cobalt-substituted ferrite nanoparticles using reverse micelles
(2005-09)
With the objective of developing a magnetic nanoparticle based sensor, we have
synthesized cobalt-substituted ferrite particles using reverse micelles. Reverse micelles
have been used to control the nanoparticle size. ...
Optimization of a fluid bed dryer by the implementation of a model predictive controller
(2006)
Optimization of the drying operation requires a model containing the operating variables for fluid bed dryers (FBD). Modeling of FBD is still uncertain since the drying process is unpredictable and relies on empirical ...
Modeling and control of continuous tumble mixing of granular materials
(2005-06)
An approach to automatic control of a continuous tumble mixer of powders is presented. The control system is based on an ideal model that describes the mixer dynamics where the controlled variables are the outlet flow from ...
Processing and characterization of nematic co-polymer Phba/Pet nanocomposite films via hot-melt extrusion
(2011)
In this research work, the effect of particle shape (i.e. rod-like, spherical and platellet) and concentration on the liquid crystalline structure of poly (4-benzoic acidco-ethylene terephthalate) (PHBA/PET) was evaluated ...
Synthesis and agglomeration of gold nanoparticles in reverse micelles
(2005)
Reverse micelles prepared in the system water, sodium bis-(2-ethylhexyl)
sulfoccinate (AOT), and isooctane were investigated as a templating system for the
production of gold nanoparticles from the reduction of Au (III) ...
Immobilization of myoglobin from horse skeletal muscle (Mb) and hemoglobin (Hb1) from Lucina pectinata in hydrophilic polymer networks for H2S biosensor application
(2005)
Hemeproteins are known for their spectroscopic properties which change during
the binding of specific ligands. This project envisioned the immobilization of myoglobin
from horse skeletal muscle (Mb) and hemoglobin I from ...
Autothermal reforming (ATR) for fuel cells in automotive applications
(2004)
Autothermal reforming of liquid fuels had been demonstrated to be feasible for use in fuel cell vehicles. One of the main problems with reforming systems is that the concentration product of carbon monoxide has to be less ...