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BCS class II drug dispersions in hydroxypropyl methylcellulose solutions: The effect of polymer molecular weight and drug loading on the steady-state rheology of HPMC solutions
Physical biopolymer gels are ideal candidates for the drug delivery of solid pharmaceutical drugs. Nevertheless, inclusion of particles may affect the rheology and gelation of these systems. In this work, we evaluate the ...
Effect of impeller speed on particle size distribution during high shear wet granulation process
Wet granulation is the process where powders are mixed with a binder agent which is agitated with a mixer and forms a granulated product. This process is commonly used to better the processing characteristics of a powdered ...