Now showing items 1-3 of 3
BCS class II drug dispersions in hydroxypropyl methylcellulose solutions: The effect of polymer molecular weight and drug loading on the steady-state rheology of HPMC solutions
Physical biopolymer gels are ideal candidates for the drug delivery of solid pharmaceutical drugs. Nevertheless, inclusion of particles may affect the rheology and gelation of these systems. In this work, we evaluate the ...
Rheological characterization of hydroxypropyl methylcellulose solutions: Gelation and molecular interactions with additives
The discovery and development of highly hydrophobic drugs represents an additional challenge for the pharmaceutical industry, as traditional methods of encapsulation, administration, and dosage are not always appropriate. ...
Rheology and gelation of physical polymer gels
The discovery of new potent and water-insoluble drugs has emphasized the need for novel drug-delivery systems and personalized dosification. Biopolymers solutions are an alternative over conventional methods since they can ...