Now showing items 1-5 of 5
Effect of operational and design parameters on the early stages of high shear wet granulation processes
The development of new technologies, active ingredients and regulatory initiatives, has increased the need for a scientific understanding of the pharmaceutical manufacturing processes. In this context, solid dosage forms ...
Experimental and numerical study of the continuous fluidized bed dryer
Nowadays, batch fluid-bed drying is one of the most efficient drying methods for particulate material; but at the same time, it is the most energy consuming operation in the manufacturing of solid dosage forms. To minimize ...
Automation of a fluid bed dryer using multi-variant near infrared spectra and model predictive control
The Fluidized Bed Dryer (FBD) is a common unit used in the pharmaceutical industry for its unique advantages when working with powders. With recent development in technology and environmental awareness, a desire to optimize ...
Effect of impeller speed on particle size distribution during high shear wet granulation process
Wet granulation is the process where powders are mixed with a binder agent which is agitated with a mixer and forms a granulated product. This process is commonly used to better the processing characteristics of a powdered ...
Improving continuous manufacturing process reliability through feeding control system
Continuous manufacturing processes are complex systems composed of multiple unit operations where process variables and material properties interaction allow the development of soft PAT sensors. Hence, this study was focused ...