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Effect of operational and design parameters on the early stages of high shear wet granulation processes
The development of new technologies, active ingredients and regulatory initiatives, has increased the need for a scientific understanding of the pharmaceutical manufacturing processes. In this context, solid dosage forms ...
Mixing of granular materials in an oscillatory shear mixer
Mezclado es uno de los pasos más importantes en el manejo de los polvos en muchas industrias tales como en la industria química, metalúrgica, farmacéutica, alimenticia, etc., debido al gran efecto que tiene en la composición ...
Modeling of growth kinetics of wet granulation in a high shear mixer by means of image processing and analysis
Wet granulation is one of the most important operations where fine particles are agglomerated into larger granules by adding a binder. The process is used in many chemical industries including pharmaceutical, mineral ...
Effect of initial formulation conditions, process parameters and equipment design on wet granulation
Ease of administration and handling are some of the reasons to keep solid oral dosage forms as the presentation of predilection for today’s medicines. Today, pharmaceutical companies are looking for more efficient processes ...